Tom Brady made his first NFL start on September 12, 1999, in a game against the Miami Dolphins. The 22-year-old quarterback, then with the New England Patriots, completed 17 of 25 passes for 189 yards and one touchdown. The game ended in a 24-21 Patriots victory.

Brady's debut was part of a season in which the Patriots finished 11-5, missing the playoffs. However, his performance signaled the beginning of a career that would redefine the quarterback position. Over the next 25 years, Brady led the Patriots to multiple Super Bowl victories and became one of the most iconic figures in NFL history.

His 1999 start marked the start of a journey that would include 14 Pro Bowl selections, a record seven Super Bowl wins, and a reputation as one of the most clutch performers in the league. Brady's early success laid the foundation for a career that would span more than two decades.

Brady's first start remains a milestone in NFL history, symbolizing the beginning of a legacy that continues to influence the game today.